BDBM50438142 CHEMBL2409847

SMILES OC[C@H]1C[C@@H](O)CCN1CCc1ccc(Nc2nc(cs2)-c2ccc(Cl)cc2Cl)cc1

InChI Key InChIKey=XIMGKTHOXDOTSY-MOPGFXCFSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438142   

TargetSphingosine kinase 2(Mus musculus (Mouse))
Amgen

Curated by ChEMBL
LigandPNGBDBM50438142(CHEMBL2409847)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse SphK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSphingosine kinase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50438142(CHEMBL2409847)
Affinity DataIC50:  40nMAssay Description:Inhibition of purified human SphK2 assessed as inhibition of formation of [33P]-S1P after 50 mins by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed